Clinicodemographic and Stricture-Related Factors Influencing Surgical Outcomes Following One-Stage Versus Staged Buccal Mucosal Graft Urethroplasty

Open Access

Abstract

Introduction: Anterior urethral stricture is a common urological disorder that is often diagnosed and is characterised by the fibrotic tissue formation and narrowing of the urethral canal which leads to obstructive voiding symptoms, urinary infections, and a decrease in quality of life. Methods & Materials: This quasi, experimental study was carried out in Department of Urology, National Institute of Kidney Diseases & Urology (NIKDU), Dhaka, for one year from 15 June 2023 to 14 June 2024. The target population of the study was 84 male patients admitted with long, segment anterior urethral stricture. The data were analysed using SPSS Statistics for Windows, version 26.0. Result: The mean age was 38.48 ± 11.90 years in Group A and 37.64 ± 10.52 years in Group B (p = 0.596). Mean stricture length in overweight patients was 7.16 ± 3.83 cm in Group A and 6.67 ± 4.19 cm in Group B (p = 0.559), while in obese patients it was 9.25 ± 4.18 cm and 10.67 ± 3.95 cm, respectively (p = 0.113). Per-operative parameters showed significantly shorter operative time in Group A (180.47 ± 3.63 min) versus Group B (254.52 ± 8.02 min; p < 0.0001) and lower blood loss (502.38 ± 31.14 ml vs. 619.76 ± 58.91 ml; p < 0.0001), while blood transfusion requirement was comparable (8 [19%] vs. 13 [30%]; p = 0.208). Stricture site distribution was also similar, with the penile urethra most common in Group A (35.7%) and bulbo-penile urethra in Group B (35.7%; p = 0.194). Conclusion: In a comparative study of one, stage and staged buccal mucosal graft urethroplasty in patients with long, segment anterior urethral strictures, it was found that the two groups were similar with respect to age, BMI, stricture length, and anatomical site of the urethral stricture.