Comparison of Serum Lipid Profile among Different Groups of Diabetic Patients

Résumé

Introduction: Diabetes mellitus is a common endocrine and metabolic problem all over the world. Type 2 diabetic patients have an increased prevalence of dyslipidemia which commonly manifests as raised low- density lipoprotein (LDL), decreased high density lipoprotein (HDL) or elevated triglycerides (TG) levels and causes public health problem worldwide as well as in our country.

Methods and materials: This cross sectional study was conducted in the Out Patient Department of Shaheed Ziaur Rahman Medical College Hospital from July 2018 to June 2019. A total number of 90 subjects (34 males and 56 females) were selected with the age above 18 year on the basis of exclusion and inclusion criteria. Data were collected in a predesigned structured questionnaire form by us.

Result:  In our study, 57.9% male diabetic patients on therapy and 46.7% male newly diagnosed diabetic patients had dyslipidemia. There were no significant difference observed between lipid profile of diabetic patients on therapy and newly diagnosed diabetic patients. In our study, 15.8% male diabetic patients on therapy and 100% male newly diagnosed diabetic patients had HbA_1C ≥ 6.5%. Positive correlation was found between HbA_1C levels and TG, TC, LDL but HDL level showed negative correlation with HbA_1C. 

Conclusion: There were no significant difference between lipid profile of diabetic patients on therapy and newly diagnosed diabetic patients but statistically significant difference was found between HbA_1C levels of diabetic patients on therapy and newly diagnosed diabetic patients. The pattern of diabetic dyslipidemia was high triglycerides and low high density lipoprotein.